[In vitro evaluation of Candida albicans adherence and growth on GC and acropars soft liners]

Adherence and growth of Candida albicanson denture soft lining materials can result in clinical problems, and deteriorations of the materials. Prevalence of denture stomatitis in association with candida albicans has been reported to range between 11%-67%. The aim of this study was to evaluate the adherence and growth of Candida albicanson two type of denture soft liners [GC and Acropars] and comparison to control group [Acropars acryl]. Twenty-two specimens of each soft lining material and 10 acrylic specimens [polished and not polished] were made and incubated in a suspension of Candida albicans. After rinsing, the specimens were stained with acridine orange and examined under fluorescent microscope. For statistical analysis One-way ANOVA and Post Hoc, TukeyHSD tests were used. The highest and the least adhesion and growth were found in the not polished and the polished groups respectively. Also, adherence and growth on Acropars soft liner was significantly more than GC soft liner [p<0.05]. Significant difference was found between polished and not polished acryl [p<0.05]. According to results, precise attention in selection of correct material with the lowest side effects and it's production steps seems mandatory

primary evaluation of live oocyst vaccine for immunization of chick against coccidiosis and the role of vitamin E on immune response

In the present study a series of experiments was performed under battery condition, two groups of chicks of 4 weeks age were vaccinated with mixed oocyst at high and low level once was kept free of infection as a control following a challenge infection to each group the result showed an established immunity compared to their respective uninfected control. In recent years report of coccidia vaccine developing showed that the best way of vaccination is administered to chicks in the water. In order to develop the vaccine diluent, the mixture of some gelatin used to correct the density of solution and on this basis the oocyst mixture is properly mixed in the diluent. The results demonstrated that as long as chick have enough appetite dietery supplementation with vitamin E 100mg/kg feed can prevent oocyst shedding compared to the control group which did not receive vitamin E. It seems the development of immunity of vaccinated chicks was increased when vitamin E added at level above those recommended as nutritional requirements

[Resistance development of field isolated eimeria spp. against some anticoccidial drugs]

There is no doubt that coccidiosis is a common and an important disease in the domestic fowl. It has been shown that the disease has brought about great losses in the poultry industry of Iran. Medication current by anticoccidial drug in the chicken has been started about 80 years ago in Iran, in recent years reports of coccidial agents developing resistance to anticoccidial drugs have been increased. The aim of this study was to determine the sensitivity of field isolated Eimeria spp. The effect of amprolium - ethopabate and lasalocid was tested in experimentally infested chicks of 4 weeks of age. The results showed that the amprolium was unable to prevent oocyst shedding. However, lasalocid was efficient in reducing oocyst output to a very significantly low level [P<0.05]. Comparing the anticoccidial effect of sulphaquinoxaline - diaverdine against clinical condition of coccidiosis indicated that it could not inhibit Eimeria acervuling oocyst shedding but toltrazuril was highly effective against combined infection with E. acervulina, E. tenella E. maxima and E. necatrix